WRNIP1 Antikörper (AA 400-450)

Produktnummer ABIN7454746

Produktdetails anti-WRNIP1 Antikörper

Target: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Bindungsspezifität: AA 400-450

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WRNIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-WRNIP1 Antibody, Affinity Purified

Homologie: Mouse,Rat

Aufreinigung: Affinity Purified

Immunogen: between AA 400 and 450

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu WRNIP1

Target: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Andere Bezeichnung: WRNIP1 (WRNIP1 Produkte)

Synonyme: WRNIP1 antikoerper, wrnip1 antikoerper, RP11-420G6.2 antikoerper, WHIP antikoerper, bA420G6.2 antikoerper, zgc:85976 antikoerper, 4833444L21Rik antikoerper, Wrnip antikoerper, Whip antikoerper, Werner helicase interacting protein 1 antikoerper, Werner helicase interacting protein 1 L homeolog antikoerper, ATPase WRNIP1 antikoerper, WRNIP1 antikoerper, wrnip1.L antikoerper, wrnip1 antikoerper, EDI_075920 antikoerper, CpipJ_CPIJ017857 antikoerper, PITG_07216 antikoerper, VDBG_02914 antikoerper, Wrnip1 antikoerper, PGTG_08805 antikoerper

Hintergrund: Background: WRNIP1 (Werner helicase interacting protein 1) was identified as a protein that interacts with the N-terminal region of Werner protein (WRN). WRN is a RecQ DNA helicase important to DNA repair and is the causative gene of Werner syndrome (WS), an autosomal recessive disease characterized by premature aging. WRNIP1 has been shown to interact with DNA polymerase delta (pol delta) and play a role in pol delta-mediated DNA synthesis. Additionally, WRNIP1 has been shown to interact with polyubiquitin chains indicating a link between ubiquitination and the DNA repair pathway.

Gen-ID: 56897

NCBI Accession: NP_064520

UniProt: Q96S55