CSTF2T Antikörper (AA 566-616)
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- Target Alle CSTF2T Antikörper anzeigen
- CSTF2T (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T))
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Bindungsspezifität
- AA 566-616
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CSTF2T Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Verwendungszweck
- Rabbit anti-CSTF2T/TauCSTF64 Antibody, Affinity Purified
- Homologie
- Mouse
- Aufreinigung
- Affinity Purified
- Immunogen
- between AA 566 and 616
- Isotyp
- IgG
- Top Product
- Discover our top product CSTF2T Primärantikörper
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- Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- CSTF2T (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T))
- Andere Bezeichnung
- CSTF2T/TauCSTF64 (CSTF2T Produkte)
- Synonyme
- 64kDa antikoerper, C77975 antikoerper, tCstF-64 antikoerper, tauCstF-64 antikoerper, CstF-64T antikoerper, cleavage stimulation factor, 3' pre-RNA subunit 2, tau antikoerper, cleavage stimulation factor subunit 2 tau variant antikoerper, cleavage stimulation factor subunit 2, tau variant antikoerper, Cstf2t antikoerper, CSTF2T antikoerper
- Hintergrund
- Background: CSTF2T, also known as tauCSTF-64, is a paralog of CstF-64, a component of the cleavage stimulation factor (CstF) that processes 3'-end formation and polyadenylation of mRNAs. The human CSTF2T/TauCSTF64 gene is located at 10q22-23, a site associated with neurological problems and male infertility. CSTF2T is expressed in all tissues and throughout meiosis in male germ cells. CstF-64 is also expressed ubiquitously, however because it is located on the X chromosome, its expression is temporarily silenced in germ cells by meiotic sex chromosome inactivation. During this inactivation, it is hypothesized that CSTF2T/TauCSTF64 can compensate for the loss of CstfF-64 expression. Recently, targeted disruption of CSTF2T/TauCSTF64 in mice has been shown to cause aberrant spermatogenesis and infertility providing more evidence for its importance in spermatogenesis.
- Gen-ID
- 23283
- NCBI Accession
- NP_056050
- UniProt
- Q9H0L4
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