CENPF Antikörper (AA 2350-2400)

Produktnummer ABIN7454765

Produktdetails anti-CENPF Antikörper

Target: CENPF (Centromere Protein F (CENPF))

Bindungsspezifität: AA 2350-2400

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-CENP-F/Mitosin Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 2350 and 2400

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu CENPF

Target: CENPF (Centromere Protein F (CENPF))

Andere Bezeichnung: CENP-F/Mitosin (CENPF Produkte)

Synonyme: LOC100222985 antikoerper, 6530404A22Rik antikoerper, AI325968 antikoerper, CENF antikoerper, Lek1 antikoerper, PRO1779 antikoerper, mitosin antikoerper, im:7140452 antikoerper, im:7144238 antikoerper, im:7154719 antikoerper, im:7156761 antikoerper, si:ch211-152h14.2 antikoerper, hcp-1 antikoerper, CMF1 antikoerper, centromere protein F antikoerper, CENPF antikoerper, Cenpf antikoerper, cenpf antikoerper

Hintergrund: Background: Centromere protein F (CENP-F) is a microtubule binding protein and component of the kinetochore. It is essential for kinetochore attachment, chromosome alignment, and the spindle checkpoint. CENP-F appears to be important to the association of the NudE-related proteins Ndel1 and Nde1 to the Lis1/dynein motor complex and their role in kinetochore function. CENP-F is a farnesylated protein and the farnesylation of CENP-F appears to be central to its role in mediating kinetochore-microtubule interactions as well as its degradation after mitosis. Recently, CENP-F expression has been correlated with markers of poor outcome in breast cancer.

Gen-ID: 1063

UniProt: P49454

Pathways: Chromatin Binding, M Phase, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion