PUS1 Antikörper (AA 377-427)
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- Target Alle PUS1 Antikörper anzeigen
- PUS1 (Pseudouridylate Synthase 1 (PUS1))
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Bindungsspezifität
- AA 377-427
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PUS1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Verwendungszweck
- Rabbit anti-PUS1 Antibody, Affinity Purified
- Aufreinigung
- Affinity Purified
- Immunogen
- between AA 377 and 427
- Isotyp
- IgG
- Top Product
- Discover our top product PUS1 Primärantikörper
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anti-Pseudouridylate Synthase 1 (PUS1) (AA 1-399) antibody
PUS1 Reaktivität: Human WB, ELISA, IP, IF Wirt: Maus Monoclonal 3A3 unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) antibodyPUS1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) (AA 322-350), (C-Term) antibodyPUS1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB32559 unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) (AA 1-399) antibodyPUS1 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) (AA 1-427) antibodyPUS1 Reaktivität: Human WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) (AA 88-137) antibodyPUS1 Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Schaf, Rind (Kuh), Hamster, Huhn, Affe, Schwein, Xenopus laevis, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) (AA 308-427) antibodyPUS1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) (AA 21-70) antibodyPUS1 Reaktivität: Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) (C-Term) antibodyPUS1 Reaktivität: Maus, Ratte, Hamster WB Wirt: Kaninchen Polyclonal unconjugated
anti-Pseudouridylate Synthase 1 (PUS1) (N-Term) antibodyPUS1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- PUS1 (Pseudouridylate Synthase 1 (PUS1))
- Andere Bezeichnung
- PUS1 (PUS1 Produkte)
- Synonyme
- PUS1 antikoerper, A730013B20Rik antikoerper, MPUS1 antikoerper, mPus1p antikoerper, MLASA1 antikoerper, pseudouridylate synthase 1 antikoerper, pseudouridylate synthase 1, putative antikoerper, pseudouridine synthase 1 antikoerper, PUS1 antikoerper, PVX_093530 antikoerper, PKH_011400 antikoerper, Pus1 antikoerper
- Hintergrund
- Background: Pus1 (pseudouridylate synthase 1) is an enzyme that converts uridine to pseudouridine in non-coding RNA substrates. Pus1 modifies uridines at specific positions in a subset of tRNAs. Pseudouridylation is known to affect the structure of tRNAs and stabilize base-stacking and base-pairing in the anticodon loop. Pus1 activity is important for proper folding and function of tRNAs. Pus1 has also been shown to pseudouridylate SRA (steroid receptor RNA activator) and function as a coactivator. Defects in pseudouridylation are associated with the human disease, MLASA (myopathy with lactic acidosis and sideroblastic anemia), an autosomal recessive oxidative phosphorylataion disorder specific to skeletal muscle and bone marrow.
- Gen-ID
- 80324
- NCBI Accession
- NP_079491
- UniProt
- Q9Y606
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