XPA Antikörper (AA 1-50)

Produktnummer ABIN7454782

Produktdetails anti-XPA Antikörper

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Bindungsspezifität: AA 1-50

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-XPA Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 1 and 50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:200 to 1:1000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu XPA

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Andere Bezeichnung: XPA (XPA Produkte)

Synonyme: CG6358 antikoerper, DhR14 antikoerper, DhXPA antikoerper, DmXPA antikoerper, Dmel\\CG6358 antikoerper, Dxpa antikoerper, EG:EG0007.8 antikoerper, XPAC antikoerper, XPA_DROME antikoerper, Xpa antikoerper, dmXPA antikoerper, dxpa antikoerper, XP1 antikoerper, AI573865 antikoerper, Xpac antikoerper, xpac antikoerper, xxpa antikoerper, Xeroderma pigmentosum group A-like antikoerper, XPA, DNA damage recognition and repair factor antikoerper, xeroderma pigmentosum, complementation group A antikoerper, xeroderma pigmentosum, complementation group A L homeolog antikoerper, Xpac antikoerper, XPA antikoerper, Xpa antikoerper, xpa.L antikoerper

Hintergrund: Background: Mutations in XPA (xeroderma pigmentosum group A-complementing protein) are the cause of xeroderma pigmentosum A (XP-A), an autosomal recessive disease that is mainly characterized by a susceptibility to UV-induced skin cancer and in some cases neurological abnormalities. XPA is one of seven XP complementation groups that have been identified. The XP complementation groups represent genes critical to the nucleotide excision repair (NER) pathway. XPA is thought to function in the recognition of DNA damage and as a processivity factor for XPF and XPG.

Gen-ID: 7507

NCBI Accession: NP_000371

UniProt: P23025

Pathways: DNA Reparatur