UBR4 Antikörper (AA 1350-1400)
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- Target Alle UBR4 Antikörper anzeigen
- UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))
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Bindungsspezifität
- AA 1350-1400
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser UBR4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Verwendungszweck
- Rabbit anti-p600 Antibody, Affinity Purified
- Aufreinigung
- Affinity Purified
- Immunogen
- between AA 1350 and 1400
- Isotyp
- IgG
- Top Product
- Discover our top product UBR4 Primärantikörper
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- Applikationshinweise
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IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2-10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- UBR4 (Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4))
- Andere Bezeichnung
- p600 (UBR4 Produkte)
- Synonyme
- ZUBR1 antikoerper, RBAF600 antikoerper, p600 antikoerper, 1810009A16Rik antikoerper, A930005E13Rik antikoerper, D930005K06Rik antikoerper, Gm1032 antikoerper, Gm1666 antikoerper, N28143 antikoerper, Zubr1 antikoerper, mKIAA0462 antikoerper, Rbaf600 antikoerper, ubiquitin protein ligase E3 component n-recognin 4 antikoerper, E3 ubiquitin-protein ligase UBR4 antikoerper, UBR4 antikoerper, Ubr4 antikoerper, LOC100511934 antikoerper
- Hintergrund
- Background: p600 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. It recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, p600 forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Additionally p600 regulates integrin-mediated signaling and may play a role in activation of FAK in response to cell-matrix interactions [taken from the Universal Protein Resource (UniProt) Q5T4S7].
- Gen-ID
- 23352
- NCBI Accession
- NP_065816
- UniProt
- Q5T4S7
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