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Rekombinanter CEACAM1/5 Antikörper (AA 35-433)

CEACAM1/5 Reaktivität: Human WB, FACS, IP, ICC, IHC (fp) Wirt: Kaninchen Monoclonal BLR032F unconjugated Recombinant Antibody
Produktnummer ABIN7455139
  • Target Alle CEACAM1/5 Produkte
    CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))
    Antikörpertyp
    Recombinant Antibody
    Bindungsspezifität
    • 1
    • 1
    • 1
    AA 35-433
    Reaktivität
    Human
    Wirt
    • 8
    • 4
    Kaninchen
    Klonalität
    • 10
    • 2
    Monoklonal
    Konjugat
    • 11
    • 1
    Dieser CEACAM1/5 Antikörper ist unkonjugiert
    Applikation
    • 7
    • 6
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    Verwendungszweck
    Rabbit anti-CEACAM1/5 Recombinant Monoclonal Antibody [BLR032F]
    Immunogen
    residues 35-433 (ECD)
    Klon
    BLR032F
    Isotyp
    IgG
  • Applikationshinweise

    IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 20 μL/1 mg lysate

    ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 17:40:00

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))
    Andere Bezeichnung
    CEACAM1/5 (CEACAM1/5 Produkte)
    Synonyme
    CD66e antikoerper, CEA antikoerper, carcinoembryonic antigen related cell adhesion molecule 5 antikoerper, CEACAM5 antikoerper
    Hintergrund
    Background: Carcinoembryonic antigen related cell adhesion molecules 1 and 5 (CEACAM1 and CEACAM5) are members of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. CEACAM1 was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM5 is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, CEACAM5 may regulate differentiation, apoptosis, and cell polarity.
    Gen-ID
    634, 1048
    NCBI Accession
    NP_001020083
    UniProt
    P13688, P06731
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