Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Haltbarkeit
12 months
Target
KLRC1
(Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
rNKG2A antikoerper, NKG2-A antikoerper, NKG2A antikoerper, KLRC1 antikoerper, CD159A antikoerper, NKG2 antikoerper, CD159a antikoerper, NKG2B antikoerper, killer cell lectin like receptor C1 antikoerper, NKG2-A/NKG2-B type II integral membrane protein-like antikoerper, killer cell lectin-like receptor subfamily C, member 3 antikoerper, killer cell lectin-like receptor subfamily C, member 1 antikoerper, Klrc1 antikoerper, KLRC1 antikoerper, NKG2A antikoerper, KLRC3 antikoerper
Hintergrund
CD159A, NKG2, NKG2A, Description: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.