HBEGF Antikörper

Produktnummer ABIN7490902

Produktdetails anti-HBEGF Antikörper

Target: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Fragment: Fc fragment

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser HBEGF Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Produktmerkmale: Rabbit/Human Fc chimeric IgG1

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cyt 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu HBEGF

Target: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Andere Bezeichnung: HBEGF (HBEGF Produkte)

Synonyme: hbegf antikoerper, zgc:165443 antikoerper, HBEGF antikoerper, zgc:175091 antikoerper, DTR antikoerper, DTS antikoerper, DTSF antikoerper, HEGFL antikoerper, Dtr antikoerper, GFHB antikoerper, Hb-egf antikoerper, Hegfl antikoerper, AW047313 antikoerper, Dts antikoerper, HB-EGF antikoerper, heparin-binding EGF-like growth factor b antikoerper, heparin binding EGF like growth factor antikoerper, Heparin-binding EGF-like growth factor antikoerper, heparin-binding EGF-like growth factor a antikoerper, heparin-binding EGF-like growth factor antikoerper, hbegfb antikoerper, HBEGF antikoerper, hbegf antikoerper, hbegfa antikoerper, Hbegf antikoerper

Hintergrund: DTR, DTS, DTSF, HEGFL,
Description: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.[UniProtKB/Swiss-Prot Function]

UniProt: Q99075

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung