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CCR6 Antikörper (APC)

CCR6 Reaktivität: Human FACS Wirt: Maus Monoclonal G034E3 APC
Produktnummer ABIN7456504
  • Target Alle CCR6 Antikörper anzeigen
    CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
    Reaktivität
    • 62
    • 22
    • 10
    • 3
    • 1
    Human
    Wirt
    • 40
    • 18
    • 6
    • 4
    • 2
    Maus
    Klonalität
    • 43
    • 26
    • 1
    Monoklonal
    Konjugat
    • 35
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCR6 Antikörper ist konjugiert mit APC
    Applikation
    • 28
    • 24
    • 18
    • 15
    • 13
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Klon
    G034E3
    Isotyp
    IgG2b, kappa
    Top Product
    Discover our top product CCR6 Primärantikörper
  • Applikationshinweise
    The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
    Kommentare

    Matching Isotype Control: APC Mouse IgG2b, κ Isotype Control (ABIN7469796)

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.05 % Proclin300, 1 % BSA
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • Target
    CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
    Andere Bezeichnung
    CD196/CCR6 (CCR6 Produkte)
    Synonyme
    BN-1 antikoerper, C-C CKR-6 antikoerper, CC-CKR-6 antikoerper, CCR-6 antikoerper, CD196 antikoerper, CKR-L3 antikoerper, CKRL3 antikoerper, CMKBR6 antikoerper, DCR2 antikoerper, DRY6 antikoerper, GPR29 antikoerper, GPRCY4 antikoerper, STRL22 antikoerper, Cmkbr6 antikoerper, KY411 antikoerper, C-C motif chemokine receptor 6 antikoerper, chemokine (C-C motif) receptor 6 antikoerper, CCR6 antikoerper, Ccr6 antikoerper
    Hintergrund
    CKRL3, CMKBR6, GPR29, STRL22,GPRCY4,CCR6, also known as CD196/CCR6, is a chemokine receptor that is expressed on immature dendritic cells, B lymphocytes, and memory T cells. CCR6 binds CCL20, although members of the β defensin family also bind CCR6 with a lower affinity. CCR6 positive cells, and its ligand CCL20, have been detected in numerous organs, especially the secondary lymphoid organ. CCL20 is selectively made by the follicle-associated epithelium (FAE) overlying Peyers Patches (PPs) and isolated lymphoid follicles (ILFs). CCL20 contributes to the recruitment of CCR6-expressing B cells to these structures. In humans, CCR6 can function to mediate arrest of T cells on dermal endothelial cells and is highly expressed on T cells resident in both normal and psoriatic skin. CCR6 and/or CCL20 have been implicated in the pathogenesis of rheumatoid arthritis and inflammatory bowel disease. Human T cells that are able to produce IL-17 express CCR6. It suggests that CCL20 and CCR6 have a role in inflammatory diseases by recruiting Th17 cells to target tissues.
    Gen-ID
    1235
    UniProt
    P51684
    Pathways
    cAMP Metabolic Process
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