Sca-1/Ly-6A/E Antikörper (PE-Cy5.5)

Produktnummer ABIN7457452

Produktdetails anti-Sca-1/Ly-6A/E Antikörper (PE-Cy5.5)

Target: Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Sca-1/Ly-6A/E Antikörper ist konjugiert mit PE-Cy5.5

Applikation: Flow Cytometry (FACS)

Klon: D7

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Kommentare:

Matching Isotype Control: PE/Cyanine5.5 Rat IgG2a, κ Isotype Control (ABIN7469845)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Details zu Sca-1/Ly-6A/E

Target: Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

Andere Bezeichnung: Ly6A/E(Sca-1) (Ly6a Produkte)

Synonyme: Ly-6A.2 antikoerper, Ly-6A/E antikoerper, Ly-6E.1 antikoerper, Sca-1 antikoerper, Sca1 antikoerper, TAP antikoerper, lymphocyte antigen 6 complex, locus A antikoerper, Ly6a antikoerper

Hintergrund: Ly6a,Ly6,Ly-6A.2/Ly-6E.1,SCA-1,TAP,Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

Gen-ID: 110454

UniProt: P05533

Pathways: Sensory Perception of Sound, Activated T Cell Proliferation