CHD1L Antikörper (C-Term)

Produktnummer ABIN7464179

Produktdetails anti-CHD1L Antikörper

Target: CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHD1L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human CHD1L. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:5000-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: 293T , A431 , HeLa , HepG2

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu CHD1L

Target: CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))

Andere Bezeichnung: chromodomain helicase DNA binding protein 1 like (CHD1L Produkte)

Synonyme: CHD1L antikoerper, ALC1 antikoerper, CHDL antikoerper, 4432404A22Rik antikoerper, Alc1 antikoerper, Snf2p antikoerper, zgc:56084 antikoerper, chromodomain helicase DNA binding protein 1 like antikoerper, chromodomain helicase DNA binding protein 1-like antikoerper, CHD1L antikoerper, chd1l antikoerper, Chd1l antikoerper

Hintergrund: Chromodomain helicase DNA binding protein 1 like , ALC1 , CHDL,In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1, MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied by OMIM]

Molekulargewicht: 101 kDa

Gen-ID: 9557

UniProt: Q86WJ1