CENPF Antikörper (AA 1759-2093)

Produktnummer ABIN7464494

Produktdetails anti-CENPF Antikörper

Target: CENPF (Centromere Protein F (CENPF))

Bindungsspezifität: AA 1759-2093

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CENPF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)

Kreuzreaktivität: Human

Aufreinigung: Protein G purified

Immunogen: Protein fragment expressed in E. coli corresponding to amino acids 1759-2093.

Klon: 14C10 1D8

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB: 1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HeLa (G2 phase)

Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, No Preservative

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu CENPF

Target: CENPF (Centromere Protein F (CENPF))

Andere Bezeichnung: centromere protein F (CENPF Produkte)

Hintergrund: Centromere protein F , CENF , CILD31 , PRO1779 , STROMS , hcp-1,This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. [provided by RefSeq, Jul 2008]

Molekulargewicht: 358 kDa

Gen-ID: 1063

UniProt: P49454

Pathways: Chromatin Binding, M Phase, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion