CARD10 Antikörper

Produktnummer ABIN7464787

Produktdetails anti-CARD10 Antikörper

Target: CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CARD10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the center region of human CARD10. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: mouse heart

Validation: KO/KD, Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.25 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu CARD10

Target: CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

Andere Bezeichnung: caspase recruitment domain family member 10 (CARD10 Produkte)

Synonyme: CARD10 antikoerper, BIMP1 antikoerper, CARMA3 antikoerper, AI449026 antikoerper, Bimp1 antikoerper, Carma3 antikoerper, caspase recruitment domain family, member 10 antikoerper, caspase recruitment domain family member 10 antikoerper, Card10 antikoerper, CARD10 antikoerper

Hintergrund: Caspase recruitment domain family member 10 , BIMP1 , CARMA3,The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB, see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM]

Molekulargewicht: 116 kDa

Gen-ID: 29775

UniProt: Q9BWT7

Pathways: S100 Proteine