USP20 Antikörper
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- Target Alle USP20 Antikörper anzeigen
- USP20 (Ubiquitin Specific Peptidase 20 (USP20))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser USP20 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity purified by Protein A.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human USP20. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product USP20 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: 293T , Raji
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.98 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- USP20 (Ubiquitin Specific Peptidase 20 (USP20))
- Andere Bezeichnung
- ubiquitin specific peptidase 20 (USP20 Produkte)
- Synonyme
- USP20 antikoerper, vdu2 antikoerper, lsfr3a antikoerper, LSFR3A antikoerper, VDU2 antikoerper, hVDU2 antikoerper, 1700055M05Rik antikoerper, AI467231 antikoerper, Vdu2 antikoerper, im:7151955 antikoerper, zgc:63661 antikoerper, universal stress protein antikoerper, ubiquitin specific peptidase 20 antikoerper, ubiquitin specific peptidase 20 L homeolog antikoerper, RR_RS15875 antikoerper, USP20 antikoerper, usp20 antikoerper, Usp20 antikoerper, usp20.L antikoerper
- Hintergrund
- Ubiquitin specific peptidase 20 , LSFR3A , VDU2 , hVDU2,Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
- Molekulargewicht
- 102 kDa
- Gen-ID
- 10868
- UniProt
- Q9Y2K6
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
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