PAK1IP1 Antikörper

Produktnummer ABIN7465359

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PAK1IP1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PAK1IP1 Antikörper (ABIN7465359)

Target: PAK1IP1 (PAK1 Interacting Protein 1 (PAK1IP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAK1IP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PAK1IP1 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PAK1 interacting protein 1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A431

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PAK1IP1

Target: PAK1IP1 (PAK1 Interacting Protein 1 (PAK1IP1))

Andere Bezeichnung: PAK1 interacting protein 1

Hintergrund: PAK1 interacting protein 1 , MAK11 , PIP1 , WDR84 , bA421M1.5 , hPIP1,Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42.

Molekulargewicht: 44 kDa

Gen-ID: 55003

UniProt: Q9NWT1

Pathways: Telomere Maintenance