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CKMT1A Antikörper

CKMT1A Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7465720
  • Target Alle CKMT1A Antikörper anzeigen
    CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
    Reaktivität
    • 21
    • 7
    • 1
    Human
    Wirt
    • 17
    • 4
    Kaninchen
    Klonalität
    • 17
    • 4
    Polyklonal
    Konjugat
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    Dieser CKMT1A Antikörper ist unkonjugiert
    Applikation
    • 16
    • 15
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Creatine kinase MT. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product CKMT1A Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: H1299 , HeLa

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
    Andere Bezeichnung
    creatine kinase, mitochondrial 1A (CKMT1A Produkte)
    Synonyme
    CKMT1 antikoerper, Mt-CK antikoerper, ScCKmit antikoerper, UbCKmit antikoerper, mi-CK antikoerper, Ckmt1 antikoerper, CKMT1B antikoerper, Mia-CK antikoerper, U-MtCK antikoerper, creatine kinase, mitochondrial 1A antikoerper, creatine kinase U-type, mitochondrial-like antikoerper, creatine kinase, mitochondrial 1, ubiquitous antikoerper, creatine kinase U-type, mitochondrial antikoerper, CKMT1A antikoerper, LOC100228000 antikoerper, Ckmt1 antikoerper, LOC100725326 antikoerper
    Hintergrund
    Creatine kinase, mitochondrial 1A , CKMT1 , U-MtCK , mia-CK,Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq]
    Molekulargewicht
    47 kDa
    Gen-ID
    548596
    UniProt
    P12532
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