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BCKDHA Antikörper (C-Term)

BCKDHA Reaktivität: Human WB, IHC (p), ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7466051
  • Target Alle BCKDHA Antikörper anzeigen
    BCKDHA (Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide (BCKDHA))
    Bindungsspezifität
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 23
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 20
    • 3
    Kaninchen
    Klonalität
    • 22
    • 1
    Polyklonal
    Konjugat
    • 19
    • 2
    • 1
    • 1
    Dieser BCKDHA Antikörper ist unkonjugiert
    Applikation
    • 17
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human BCKDHA. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product BCKDHA Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: HepG2

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    BCKDHA (Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide (BCKDHA))
    Andere Bezeichnung
    branched chain keto acid dehydrogenase E1, alpha polypeptide (BCKDHA Produkte)
    Synonyme
    wu:fd20d04 antikoerper, zgc:110049 antikoerper, BCKDE1A antikoerper, MSU antikoerper, MSUD1 antikoerper, OVD1A antikoerper, BCKDA antikoerper, E1a antikoerper, 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial antikoerper, branched chain keto acid dehydrogenase E1, alpha polypeptide antikoerper, 2-oxoisovalerate dehydrogenase alpha subunit (branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha) (BCKDE1A) antikoerper, branched chain ketoacid dehydrogenase E1, alpha polypeptide antikoerper, LOC704978 antikoerper, bckdha antikoerper, BCKDHA antikoerper, BckdhA antikoerper, Bckdha antikoerper
    Hintergrund
    Branched chain keto acid dehydrogenase E1, alpha polypeptide , BCKDE1A , MSU , MSUD1 , OVD1A,The BCKDHA gene encodes the E1-alpha subunit of the branched-chain alpha-keto acid (BCAA) dehydrogenase complex (BCKD, EC 1.2.4.4), an inner-mitochondrial enzyme complex that catalyzes the oxidative decarboxylation of the branched-chain alpha-ketoacids derived from isoleucine, leucine, and valine. This reaction is the second major step in the catabolism of the branched-chain amino acids (Wynn et al., 1998 [PubMed 9582350]). The BCKD complex consists of 3 catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a homo-24-meric dihydrolipoyl transacylase (E2, MIM 248610), and a homodimeric dihydrolipoamide dehydrogenase (E3, MIM 238331). E1 is a thiamine pyrophosphate (TPP)-dependent enzyme. The reaction is irreversible and constitutes the first committed step in BCAA oxidation. The BCKDHB gene (MIM 248611) encodes the beta subunit of E1. The complex also contains 2 regulatory enzymes, a kinase and a phosphorylase.[supplied by OMIM]
    Molekulargewicht
    50 kDa
    Gen-ID
    593
    UniProt
    P12694
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