Bestrophin 1 Antikörper (C-Term)

Produktnummer ABIN7467101

Produktdetails anti-Bestrophin 1 Antikörper

Target: Bestrophin 1 (BEST1)

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Bestrophin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Bestrophin 1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: NT2D1 , PC-3 , U87-MG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu Bestrophin 1

Target: Bestrophin 1 (BEST1)

Andere Bezeichnung: bestrophin 1 (BEST1 Produkte)

Synonyme: CG6264 antikoerper, Dbest antikoerper, Dmel\\CG6264 antikoerper, anon-WO0118547.380 antikoerper, best antikoerper, dBest1 antikoerper, dbest1 antikoerper, dmBest1 antikoerper, BEST1 antikoerper, VMD2 antikoerper, best-1 antikoerper, ARB antikoerper, BEST antikoerper, BMD antikoerper, RP50 antikoerper, TU15B antikoerper, Bmd antikoerper, Vmd2 antikoerper, mBest1 antikoerper, Bestrophin 1 antikoerper, bestrophin 1 antikoerper, Best1 antikoerper, BEST1 antikoerper, best1 antikoerper, Bm1_25500 antikoerper

Hintergrund: Bestrophin 1 , ARB , BEST , BMD , Best1V1Delta2 , RP50 , TU15B , VMD2,This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

Molekulargewicht: 68 kDa

Gen-ID: 7439

UniProt: O76090