LIM Domain Binding 3 Protein Antikörper

Produktnummer ABIN7467111

Produktdetails anti-LIM Domain Binding 3 Protein Antikörper

Target: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIM Domain Binding 3 Protein Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human LDB3. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: NT2D1 , RD , rat muscle , mouse muscle

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu LIM Domain Binding 3 Protein

Target: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Andere Bezeichnung: LIM domain binding 3 (LDB3 Produkte)

Synonyme: CMD1C antikoerper, CYPHER antikoerper, LDB3Z1 antikoerper, LDB3Z4 antikoerper, LVNC3 antikoerper, MFM4 antikoerper, ORACLE antikoerper, PDLIM6 antikoerper, ZASP antikoerper, AW742271 antikoerper, ldb3l antikoerper, zgc:55814 antikoerper, wu:fi31d08 antikoerper, ldb3 antikoerper, MGC52706 antikoerper, MGC75668 antikoerper, RGD1564875 antikoerper, LDB3 antikoerper, cypher antikoerper, hm:zehn1639 antikoerper, zehn1639 antikoerper, LIM domain binding 3 antikoerper, LIM domain binding 3b antikoerper, LIM domain binding 3 S homeolog antikoerper, LIM domain binding 3a antikoerper, LDB3 antikoerper, Ldb3 antikoerper, ldb3b antikoerper, ldb3.S antikoerper, ldb3 antikoerper, ldb3a antikoerper

Hintergrund: LIM domain binding 3 , CMD1C , CMH24 , CMPD3 , CYPHER , LDB3Z1 , LDB3Z4 , LVNC3 , MFM4 , ORACLE , PDLIM6 , ZASP,This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified, all isoforms have N-terminal PDZ domains while only longer isoforms (1 and 2) have C-terminal LIM domains. [provided by RefSeq]

Molekulargewicht: 77 kDa

Gen-ID: 11155

UniProt: O75112