IVNS1ABP Antikörper (C-Term)

Produktnummer ABIN7467508

Produktdetails anti-IVNS1ABP Antikörper

Target: IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IVNS1ABP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human IVNS1ABP. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: U87-MG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.57 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu IVNS1ABP

Target: IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Andere Bezeichnung: influenza virus NS1A binding protein (IVNS1ABP Produkte)

Synonyme: 1190004M08Rik antikoerper, 1700126I16Rik antikoerper, AA960440 antikoerper, HSPC068 antikoerper, ND1 antikoerper, NS-1 antikoerper, NS1-BP antikoerper, Nd1-L antikoerper, Nd1-S antikoerper, mKIAA0850 antikoerper, cb1052 antikoerper, fj23g11 antikoerper, ivns1abp antikoerper, wu:fj23g11 antikoerper, FLARA3 antikoerper, KLHL39 antikoerper, NS1BP antikoerper, fi13f08 antikoerper, fi41c09 antikoerper, wu:fi13f08 antikoerper, wu:fi41c09 antikoerper, influenza virus NS1A binding protein antikoerper, influenza virus NS1A binding protein a antikoerper, influenza virus NS1A binding protein L homeolog antikoerper, influenza virus NS1A binding protein b antikoerper, Ivns1abp antikoerper, ivns1abpa antikoerper, ivns1abp.L antikoerper, IVNS1ABP antikoerper, ivns1abpb antikoerper

Substanzklasse: Influenza Protein

Hintergrund: Influenza virus NS1A binding protein , ARA3 , FLARA3 , HSPC068 , KLHL39 , ND1 , NS-1 , NS1-BP , NS1BP,Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization, Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing, may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.

Molekulargewicht: 72 kDa

Gen-ID: 10625

UniProt: Q9Y6Y0

Pathways: Negative Regulation of intrinsic apoptotic Signaling