NLRP2 Antikörper

Produktnummer ABIN7467666

Produktdetails anti-NLRP2 Antikörper

Target: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human NALP2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu NLRP2

Target: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Andere Bezeichnung: NLR family pyrin domain containing 2 (NLRP2 Produkte)

Synonyme: CLR19.9 antikoerper, NALP2 antikoerper, NBS1 antikoerper, PAN1 antikoerper, PYPAF2 antikoerper, NLRP2 antikoerper, E330007A02Rik antikoerper, Nalp2 antikoerper, NLR family pyrin domain containing 2 antikoerper, NACHT, LRR and PYD domains-containing protein 2 antikoerper, NLR family pyrin domain containing 7 antikoerper, NLR family, pyrin domain containing 2 antikoerper, NLRP2 antikoerper, LOC100301026 antikoerper, LOC100387349 antikoerper, NLRP7 antikoerper, Nlrp2 antikoerper

Hintergrund: NLR family pyrin domain containing 2 , CLR19.9 , NALP2 , NBS1 , PAN1 , PYPAF2,NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1, MIM 147678) by Toll-like receptors (see TLR4, MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM]

Molekulargewicht: 121 kDa

Gen-ID: 55655

UniProt: Q9NX02

Pathways: Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome