HLA-DOA Antikörper

Produktnummer ABIN7467728

Produktdetails anti-HLA-DOA Antikörper

Target: HLA-DOA (HLA Class II DO alpha (HLA-DOA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HLA-DOA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human HLA-DOA. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.64 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu HLA-DOA

Target: HLA-DOA (HLA Class II DO alpha (HLA-DOA))

Andere Bezeichnung: major histocompatibility complex, class II, DO alpha (HLA-DOA Produkte)

Synonyme: HLA-DNA antikoerper, HLA-DZA antikoerper, HLADZ antikoerper, major histocompatibility complex, class II, DO alpha antikoerper, HLA-DOA antikoerper

Hintergrund: Major histocompatibility complex, class II, DO alpha , HLA-DNA , HLA-DZA , HLADZ,HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq]

Molekulargewicht: 28 kDa

Gen-ID: 3111

UniProt: P06340

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response