ATR Antikörper (AA 710-1100)
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- Target Alle ATR Antikörper anzeigen
- ATR (Ataxia Telangiectasia and Rad3 Related (ATR))
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Bindungsspezifität
- AA 710-1100
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ATR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Functional Studies (Func)
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- Protein G purified
- Immunogen
- Recombinant fragment, corresponding to amino acids 710-1100 of Human ATR.
- Klon
- 2B5
- Isotyp
- IgG1
- Top Product
- Discover our top product ATR Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: Raji , Raji nuclear extract Validation: Orthogonal
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS, No Preservative
- Konservierungsmittel
- Without preservative
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- ATR (Ataxia Telangiectasia and Rad3 Related (ATR))
- Andere Bezeichnung
- ATR serine/threonine kinase (ATR Produkte)
- Synonyme
- ATR antikoerper, si:dkey-231j24.1 antikoerper, FCTCS antikoerper, FRP1 antikoerper, MEC1 antikoerper, SCKL antikoerper, SCKL1 antikoerper, XATR antikoerper, frp1 antikoerper, mec1 antikoerper, sckl antikoerper, sckl1 antikoerper, ARABIDOPSIS THALIANA ATAXIA TELANGIECTASIA-MUTATED AND RAD3-RELATED antikoerper, ATATR antikoerper, ATRAD3 antikoerper, Ataxia telangiectasia-mutated and RAD3-related antikoerper, MHK7.5 antikoerper, MHK7_5 antikoerper, ataxia telangiectasia and Rad3 related antikoerper, ATR serine/threonine kinase antikoerper, ATR serine/threonine kinase L homeolog antikoerper, Ataxia telangiectasia-mutated and RAD3-like protein antikoerper, Atr antikoerper, ATR antikoerper, atr antikoerper, atr.L antikoerper
- Hintergrund
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Synonyms: ATR serine/threonine kinase , FCTCS , FRP1 , MEC1 , SCKL , SCKL1
Background: The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
- Molekulargewicht
- 301 kDa
- Gen-ID
- 545
- UniProt
- Q13535
- Pathways
- p53 Signalweg, Apoptose, DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus
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