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ATR Antikörper (AA 710-1100)

ATR Reaktivität: Human WB, IP, ICC, IF, Func Wirt: Maus Monoclonal 2B5 unconjugated
Produktnummer ABIN7467985
  • Target Alle ATR Antikörper anzeigen
    ATR (Ataxia Telangiectasia and Rad3 Related (ATR))
    Bindungsspezifität
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 710-1100
    Reaktivität
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 6
    • 1
    Maus
    Klonalität
    • 6
    • 1
    Monoklonal
    Konjugat
    • 7
    Dieser ATR Antikörper ist unkonjugiert
    Applikation
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Functional Studies (Func)
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    Protein G purified
    Immunogen
    Recombinant fragment, corresponding to amino acids 710-1100 of Human ATR.
    Klon
    2B5
    Isotyp
    IgG1
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  • Applikationshinweise
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: Raji , Raji nuclear extract Validation: Orthogonal

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, No Preservative
    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    ATR (Ataxia Telangiectasia and Rad3 Related (ATR))
    Andere Bezeichnung
    ATR serine/threonine kinase (ATR Produkte)
    Synonyme
    ATR antikoerper, si:dkey-231j24.1 antikoerper, FCTCS antikoerper, FRP1 antikoerper, MEC1 antikoerper, SCKL antikoerper, SCKL1 antikoerper, XATR antikoerper, frp1 antikoerper, mec1 antikoerper, sckl antikoerper, sckl1 antikoerper, ARABIDOPSIS THALIANA ATAXIA TELANGIECTASIA-MUTATED AND RAD3-RELATED antikoerper, ATATR antikoerper, ATRAD3 antikoerper, Ataxia telangiectasia-mutated and RAD3-related antikoerper, MHK7.5 antikoerper, MHK7_5 antikoerper, ataxia telangiectasia and Rad3 related antikoerper, ATR serine/threonine kinase antikoerper, ATR serine/threonine kinase L homeolog antikoerper, Ataxia telangiectasia-mutated and RAD3-like protein antikoerper, Atr antikoerper, ATR antikoerper, atr antikoerper, atr.L antikoerper
    Hintergrund

    Synonyms: ATR serine/threonine kinase , FCTCS , FRP1 , MEC1 , SCKL , SCKL1

    Background: The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]

    Molekulargewicht
    301 kDa
    Gen-ID
    545
    UniProt
    Q13535
    Pathways
    p53 Signalweg, Apoptose, DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus
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