KDELR1 Antikörper
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- Target Alle KDELR1 Antikörper anzeigen
- KDELR1 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KDELR1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Hamster
- Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human KDEL receptor. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product KDELR1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.729 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- KDELR1 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))
- Andere Bezeichnung
- KDEL endoplasmic reticulum protein retention receptor 1 (KDELR1 Produkte)
- Synonyme
- ERD2 antikoerper, ERD2.1 antikoerper, HDEL antikoerper, PM23 antikoerper, 8030486F04Rik antikoerper, AW215843 antikoerper, Erd2.1 antikoerper, KDEL endoplasmic reticulum protein retention receptor 1 antikoerper, KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 antikoerper, KDELR1 antikoerper, Kdelr1 antikoerper
- Hintergrund
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Synonyms: KDEL endoplasmic reticulum protein retention receptor 1 , ERD2 , ERD2.1 , HDEL , PM23
Background: Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product. [provided by RefSeq]
- Molekulargewicht
- 25 kDa
- Gen-ID
- 10945
- UniProt
- P24390
- Pathways
- Maintenance of Protein Location
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