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LILRB3 Antikörper

LILRB3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7468542
  • Target Alle LILRB3 Antikörper anzeigen
    LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))
    Reaktivität
    • 19
    • 13
    • 1
    Human
    Wirt
    • 30
    • 1
    • 1
    Kaninchen
    Klonalität
    • 30
    • 2
    Polyklonal
    Konjugat
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LILRB3 Antikörper ist unkonjugiert
    Applikation
    • 14
    • 12
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human LILRB3. The exact sequence is proprietary.
    Isotyp
    IgG
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  • Applikationshinweise
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: Jurkat

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))
    Andere Bezeichnung
    leukocyte immunoglobulin like receptor B3 (LILRB3 Produkte)
    Synonyme
    CD85A antikoerper, HL9 antikoerper, ILT-5 antikoerper, ILT5 antikoerper, LILRA6 antikoerper, LIR-3 antikoerper, LIR3 antikoerper, PIRB antikoerper, Gp91 antikoerper, Lilrb3 antikoerper, PIR-B antikoerper, Pirb antikoerper, NILR-1 antikoerper, LILRB3 antikoerper, leukocyte immunoglobulin like receptor B3 antikoerper, paired Ig-like receptor B antikoerper, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 antikoerper, LILRB3 antikoerper, Pirb antikoerper
    Hintergrund

    Synonyms: leukocyte immunoglobulin like receptor B3 , CD85A , HL9 , ILT-5 , ILT5 , LILRA6 , LIR-3 , LIR3 , PIR-B , PIRB

    Background: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

    Molekulargewicht
    69 kDa
    Gen-ID
    11025
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