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LIN7A Antikörper

LIN7A Reaktivität: Human WB, IF, ICC Wirt: Maus Monoclonal GT377 unconjugated
Produktnummer ABIN7468549
  • Target Alle LIN7A Antikörper anzeigen
    LIN7A (Lin-7 Homolog A (LIN7A))
    Reaktivität
    • 30
    • 6
    • 4
    • 1
    • 1
    Human
    Wirt
    • 27
    • 3
    Maus
    Klonalität
    • 29
    • 1
    Monoklonal
    Konjugat
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser LIN7A Antikörper ist unkonjugiert
    Applikation
    • 26
    • 20
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Human
    Aufreinigung
    Affinity purified by Protein G.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human LIN7A. The exact sequence is proprietary.
    Klon
    GT377
    Isotyp
    IgG2b
    Top Product
    Discover our top product LIN7A Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: MCF-7 , MDA-MB-231

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, No Preservative
    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    LIN7A (Lin-7 Homolog A (LIN7A))
    Andere Bezeichnung
    lin-7 homolog A, crumbs cell polarity complex component (LIN7A Produkte)
    Synonyme
    LIN-7A antikoerper, LIN7 antikoerper, MALS-1 antikoerper, TIP-33 antikoerper, VELI1 antikoerper, lin7b antikoerper, zgc:73090 antikoerper, AI848705 antikoerper, Veli antikoerper, Veli1 antikoerper, lin-7 homolog A, crumbs cell polarity complex component antikoerper, lin-7 homolog A (C. elegans) antikoerper, LIN7A antikoerper, lin7a antikoerper, Lin7a antikoerper
    Hintergrund

    Synonyms: lin-7 homolog A, crumbs cell polarity complex component , LIN-7A , LIN7 , MALS-1 , MALS1 , TIP-33 , VELI1

    Background: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

    Molekulargewicht
    26 kDa
    Gen-ID
    8825
    UniProt
    O14910
    Pathways
    Synaptic Membrane
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