POLE3 Antikörper

Produktnummer ABIN7468761

Produktdetails anti-POLE3 Antikörper

Target: POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLE3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the center region of human DNA polymerase epsilon 3. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: 293T Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.01 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu POLE3

Target: POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))

Andere Bezeichnung: DNA polymerase epsilon 3, accessory subunit (POLE3 Produkte)

Synonyme: NCU04548.1 antikoerper, GB14966 antikoerper, zgc:73351 antikoerper, 1810034K18Rik antikoerper, YBL1 antikoerper, CHARAC17 antikoerper, CHRAC17 antikoerper, p17 antikoerper, DNA polymerase epsilon 3, accessory subunit antikoerper, polymerase (DNA directed), epsilon 3, accessory subunit antikoerper, DNA polymerase epsilon antikoerper, DNA polymerase epsilon p17 subunit antikoerper, DNA polymerase epsilon subunit 3 antikoerper, polymerase (DNA directed), epsilon 3 (p17 subunit) antikoerper, POLE3 antikoerper, pole3 antikoerper, NCU04548 antikoerper, CpipJ_CPIJ008666 antikoerper, Bm1_04865 antikoerper, Bm1_07285 antikoerper, CTRG_00708 antikoerper, LOAG_09571 antikoerper, LOC726923 antikoerper, Pole3 antikoerper

Hintergrund:

Synonyms: DNA polymerase epsilon 3, accessory subunit , CHARAC17 , CHRAC17 , CHRAC2 , YBL1 , p17

Background: POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM]

Molekulargewicht: 17 kDa

Gen-ID: 54107

UniProt: Q9NRF9

Pathways: DNA Reparatur