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COX10 Antikörper

COX10 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7469298
  • Target Alle COX10 Antikörper anzeigen
    COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))
    Reaktivität
    • 38
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 36
    • 2
    Kaninchen
    Klonalität
    • 38
    Polyklonal
    Konjugat
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COX10 Antikörper ist unkonjugiert
    Applikation
    • 29
    • 17
    • 17
    • 14
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human COX10. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product COX10 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: U87-MG , SK-N-SH , IMR-32 , SK-N-AS

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))
    Andere Bezeichnung
    COX10 (COX10 Produkte)
    Synonyme
    2410004F01Rik antikoerper, AU042636 antikoerper, im:7145568 antikoerper, im:7157205 antikoerper, wu:fb18a03 antikoerper, F4I1.50 antikoerper, F4I1_50 antikoerper, cytochrome c oxidase 10 antikoerper, Cox10 antikoerper, cytochrome c oxidase assembly protein 10 antikoerper, COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor antikoerper, COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor L homeolog antikoerper, COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor antikoerper, cytochrome c oxidase 10 antikoerper, protoheme IX farnesyltransferase, mitochondrial antikoerper, Cox10 antikoerper, cox10 antikoerper, cox10.L antikoerper, COX10 antikoerper, LOC100732273 antikoerper
    Hintergrund

    Synonyms: cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10

    Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion. [provided by RefSeq]

    Molekulargewicht
    49 kDa
    Gen-ID
    1352
    UniProt
    Q12887
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