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GATSL3 Antikörper

GATSL3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7469300
  • Target Alle GATSL3 Produkte
    GATSL3 (GATS Protein-Like 3 (GATSL3))
    Reaktivität
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 2
    Kaninchen
    Klonalität
    • 2
    Polyklonal
    Konjugat
    • 2
    Dieser GATSL3 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB)
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human GATSL3. The exact sequence is proprietary.
    Isotyp
    IgG
  • Applikationshinweise
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: MCF-7 , MDA-MB-231

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.9 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    GATSL3 (GATS Protein-Like 3 (GATSL3))
    Andere Bezeichnung
    GATSL3 (GATSL3 Produkte)
    Synonyme
    2410008K03Rik antikoerper, RGD1304774 antikoerper, cytosolic arginine sensor for mTORC1 subunit 1 antikoerper, GATS protein-like 3 antikoerper, CASTOR1 antikoerper, Gatsl3 antikoerper, Castor1 antikoerper
    Hintergrund

    Synonyms: cytosolic arginine sensor for mTORC1 subunit 1 , GATSL3

    Background: Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.

    Molekulargewicht
    36 kDa
    Gen-ID
    652968
    UniProt
    Q8WTX7
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