CD45RO Antikörper (FITC)
Kurzübersicht für CD45RO Antikörper (FITC) (ABIN7470012)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Isotyp
- IgG2a, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Matching Isotype Control: FITC Mouse IgG2a, κ Isotype Control (ABIN7469777)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- CD45RO
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Andere Bezeichnung
- CD45RO
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Hintergrund
- CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.
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Gen-ID
- 5788
Target
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