Rekombinanter Bevacizumab Antikörper
MALS verified
Reaktivität: Human
Wirt: Maus
Monoclonal
AY10
unconjugated
Recombinant Antibody
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- Target Alle Bevacizumab Produkte
- Bevacizumab
- Antikörpertyp
- Recombinant Antibody
- Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Bevacizumab Antikörper ist unkonjugiert
- Verwendungszweck
- Anti-Bevacizumab Antibody (AY10) (MALS verified, recommended for PK/PD)
- Produktmerkmale
- Anti-idiotypic Antibodies
- Güteklasse
- MALS verified
- Immunogen
- Mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Bevacizumab F(ab')2.
- Klon
- AY10
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Lagerung
- -20 °C
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- Target
- Bevacizumab
- Abstract
- Bevacizumab Produkte
- Substanzklasse
- Antibody
- Hintergrund
- A recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF). Bevacizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to VEGF. Bevacizumab is produced in a Chinese Hamster Ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin and has a molecular weight of approximately 149 kilodaltons.
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