LRRC4C Antikörper (AA 561-640) (Biotin)

Produktnummer ABIN720298

Produktdetails anti-LRRC4C Antikörper (Biotin)

Target: LRRC4C (Leucine Rich Repeat Containing 4C (LRRC4C))

Bindungsspezifität: AA 561-640

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRC4C Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Netrin G1 ligand

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu LRRC4C

Target: LRRC4C (Leucine Rich Repeat Containing 4C (LRRC4C))

Andere Bezeichnung: Netrin G1 ligand (LRRC4C Produkte)

Synonyme: 6430556C10Rik antikoerper, NGL-1 antikoerper, mKIAA1580 antikoerper, RGD1311013 antikoerper, fd12d10 antikoerper, wu:fd12d10 antikoerper, zgc:110565 antikoerper, NGL1 antikoerper, leucine rich repeat containing 4C antikoerper, Lrrc4c antikoerper, lrrc4c antikoerper, LRRC4C antikoerper

Hintergrund:

Synonyms: Leucine rich repeat containing 4C, Leucine-rich repeat-containing protein 4C, LRC4C_HUMAN, Lrrc4C, Netrin-G1 ligand, NGL 1, NGL-1, NGL1.

Background: NGL-1 is a single pass type I membrane protein that acts as a cell adhesion molecule. It contains nine leucine-rich repeats (LRR) and one Ig-like C2-type domain. NGL-1 is predominantly expressed in the striatum and the cerebral cortex of both the embryonic and adult brain. NGL-1 specifically interacts with Netrin G1 (a molecule involved in axon guidance in the developing central nervous system) via its LRR region. NGL-1 plays a role in the regulation of neurite outgrowth of developing thalamic neurons. Soluble NGL-1 inhibits thalamic axon outgrowth while NGL-1 that is bound to the surface of developing thalamocortical axons stimulates growth. NGL-1 also interacts with Whirlin possibly stablizing interstereociliar links.

Gen-ID: 22854

Pathways: Synaptic Membrane