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MORG1 Antikörper (AA 201-315) (Biotin)

wdr83 Reaktivität: Ratte, Maus WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN720477
  • Target Alle MORG1 (wdr83) Antikörper anzeigen
    MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))
    Bindungsspezifität
    • 14
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 201-315
    Reaktivität
    • 40
    • 33
    • 32
    • 1
    • 1
    • 1
    • 1
    • 1
    Ratte, Maus
    Wirt
    • 49
    • 5
    Kaninchen
    Klonalität
    • 52
    • 2
    Polyklonal
    Konjugat
    • 23
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MORG1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 39
    • 19
    • 13
    • 13
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Cow,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MAPK organizer 1
    Isotyp
    IgG
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  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))
    Andere Bezeichnung
    MAPK organizer 1 (wdr83 Produkte)
    Synonyme
    MORG1 antikoerper, 1500041N16Rik antikoerper, Morg1 antikoerper, RGD1306947 antikoerper, morg1 antikoerper, MAPK organizer 1 antikoerper, wu:fj29g04 antikoerper, zgc:92654 antikoerper, WD repeat domain 83 antikoerper, WD repeat domain containing 83 antikoerper, WD repeat domain 83 L homeolog antikoerper, WDR83 antikoerper, Wdr83 antikoerper, wdr83.L antikoerper, wdr83 antikoerper
    Hintergrund

    Synonyms: MORG1, WD repeat domain-containing protein 83, Mitogen-activated protein kinase organizer 1, MAPK organizer 1, WDR83

    Background: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.

    Gen-ID
    84292
    UniProt
    Q9BRX9
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