MORG1 Antikörper (AA 201-315) (Biotin)
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- Target Alle MORG1 (wdr83) Antikörper anzeigen
- MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))
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Bindungsspezifität
- AA 201-315
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Reaktivität
- Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MORG1 Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Maus, Ratte
- Homologie
- Human,Dog,Cow,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MAPK organizer 1
- Isotyp
- IgG
- Top Product
- Discover our top product wdr83 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))
- Andere Bezeichnung
- MAPK organizer 1 (wdr83 Produkte)
- Synonyme
- MORG1 antikoerper, 1500041N16Rik antikoerper, Morg1 antikoerper, RGD1306947 antikoerper, morg1 antikoerper, MAPK organizer 1 antikoerper, wu:fj29g04 antikoerper, zgc:92654 antikoerper, WD repeat domain 83 antikoerper, WD repeat domain containing 83 antikoerper, WD repeat domain 83 L homeolog antikoerper, WDR83 antikoerper, Wdr83 antikoerper, wdr83.L antikoerper, wdr83 antikoerper
- Hintergrund
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Synonyms: MORG1, WD repeat domain-containing protein 83, Mitogen-activated protein kinase organizer 1, MAPK organizer 1, WDR83
Background: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.
- Gen-ID
- 84292
- UniProt
- Q9BRX9
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