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Thrombomodulin Antikörper

THBD Reaktivität: Human FACS Wirt: Maus Monoclonal M80 unconjugated
Produktnummer ABIN7505855
  • Target Alle Thrombomodulin (THBD) Antikörper anzeigen
    Thrombomodulin (THBD)
    Reaktivität
    • 105
    • 34
    • 19
    • 3
    • 2
    • 1
    Human
    Wirt
    • 63
    • 53
    • 6
    • 2
    Maus
    Klonalität
    • 67
    • 57
    Monoklonal
    Konjugat
    • 55
    • 18
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Thrombomodulin Antikörper ist unkonjugiert
    Applikation
    • 76
    • 44
    • 40
    • 39
    • 25
    • 22
    • 21
    • 15
    • 14
    • 13
    • 11
    • 11
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Verwendungszweck
    Anti-Hu CD141 Purified
    Spezifität
    The mouse monoclonal antibody M80 recognizes an extracellular epitope of CD141, a 75 kDa transmembrane glycoprotein expressed mainly on macrophages, monocytes, platelets and endothelial cells.
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Immunogen
    MV4-11 cell line
    Klon
    M80
    Isotyp
    IgG1
    Top Product
    Discover our top product THBD Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-5 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    Thrombomodulin (THBD)
    Andere Bezeichnung
    CD141 (THBD Produkte)
    Synonyme
    AHUS6 antikoerper, BDCA3 antikoerper, CD141 antikoerper, THPH12 antikoerper, THRM antikoerper, TM antikoerper, AI385582 antikoerper, THBD antikoerper, HAST antikoerper, HAST3 antikoerper, M-PST antikoerper, ST1A3/ST1A4 antikoerper, ST1A5 antikoerper, STM antikoerper, TL-PST antikoerper, thrombomodulin antikoerper, sulfotransferase family 1A member 3 antikoerper, THBD antikoerper, Thbd antikoerper, SULT1A3 antikoerper
    Hintergrund
    Thrombomodulin,CD141, also known as thrombomodulin or fetomodulin, is a single chain type I transmembrane glycoprotein serving as a receptor for thrombin and as an important cofactor in the protein C anticoagulant system, but it is also involved in embryonic and atherosclerotic plaque development. CD141 is expressed mainly on macrophages, monocytes, a subpopulation of myeloid dendritic cells, on platelets and endothelial cells, but also e.g. on keratinocytes (epithelium). After binding to thrombin, CD141 activates protein C, which degrades clotting factors Va and VIIIa, and as a consequence the amount of thrombin is reduced. Mutations in the CD141 gene can cause a thromboembolic disease known as inherited thrombophilia.,Thrombomodulin, fetomodulin, THBD, THRM, THPH12, TM
    Gen-ID
    7056
    UniProt
    P07204
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