The mouse monoclonal antibody H5 recognizes an epitope within extracellular part of CD307c, a transmembrane glycoprotein expressed mainly on NK cells, and T and B cell subsets.
Aufreinigung
Purified by protein-A affinity chromatography.
Immunogen
DNA-immunization followed by a boost with CD307c transfected cells
CD307c antikoerper, FCRH3 antikoerper, IFGP3 antikoerper, IRTA3 antikoerper, SPAP2 antikoerper, fcrh3 antikoerper, ifgp3 antikoerper, irta3 antikoerper, spap2 antikoerper, xfl1.2 antikoerper, Fc receptor like 3 antikoerper, Fc receptor-like 3 L homeolog antikoerper, Fc receptor-like 3 antikoerper, Fc receptor-like 3 S homeolog antikoerper, FCRL3 antikoerper, fcrl3.L antikoerper, fcrl3 antikoerper, fcrl3.S antikoerper
Hintergrund
Fc receptor like 3,CD307c is a type I transmembrane glycoprotein of the Fc receptor family. It contains both ITAM and ITIM motifs in its cytoplasmic domain. CD307c is expressed on the surface of NK cells, and T, Treg, B and plasma cell subsets. It seems to play a role in the regulation of immune response. Defects in CD307c function can result in autoimmune diseases, e.g. rheumatoid arthritis or systemic lupus erythematosus.,FcRL3, IRTA3