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HLA-C Antikörper (PE)

HLA-C Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal DT-9 PE
Produktnummer ABIN7505981
  • Target Alle HLA-C Antikörper anzeigen
    HLA-C (Major Histocompatibility Complex Class I C (HLA-C))
    Reaktivität
    • 57
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Non-Human Primate
    Wirt
    • 48
    • 9
    Maus
    Klonalität
    • 50
    • 7
    Monoklonal
    Konjugat
    • 23
    • 9
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HLA-C Antikörper ist konjugiert mit PE
    Applikation
    • 32
    • 29
    • 11
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    Flow Cytometry (FACS)
    Verwendungszweck
    Anti-HLA-C PE
    Spezifität
    The mouse monoclonal antibody DT-9 recognizes an extracellular epitope on HLA-C member of MHC class I molecules. It does not crossreact with HLA-A or HLA-B allotypes.
    Aufreinigung
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    Purified MHC class I molecules of tamarin origin
    Klon
    DT-9
    Isotyp
    IgG2b
    Top Product
    Discover our top product HLA-C Primärantikörper
  • Applikationshinweise
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target
    HLA-C (Major Histocompatibility Complex Class I C (HLA-C))
    Andere Bezeichnung
    HLA-C (HLA-C Produkte)
    Synonyme
    D6S204 antikoerper, HLA-JY3 antikoerper, HLC-C antikoerper, PSORS1 antikoerper, major histocompatibility complex, class I, C antikoerper, HLA-C antikoerper
    Hintergrund
    Major histocompatibility complex, class I, C,HLA-C, a member of MHC class I glycoproteins, is one of polymorphysm typing targets, which are important for transplantation. The HLA system plays an important role in the occurrence and outcome of infectious diseases. The structural spike and the nucleocapsid proteins of the novel coronavirus SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19), are reported to contain multiple Class I epitopes with predicted HLA restrictions. Individual HLA genetic variation may help explain different immune responses to a virus across a population. It has been described that HLA-C interacts with human herpesvirus 8 MIR1 protein.,HLC-C, D6S204, PSORS1, HLA-JY3
    Gen-ID
    3107
    UniProt
    P10321
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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