TOMM34 Antikörper

Produktnummer ABIN7506025

Produktdetails anti-TOMM34 Antikörper

Target: TOMM34 (Translocase of Outer Mitochondrial Membrane 34 (TOMM34))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TOMM34 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Verwendungszweck: Anti-Hu Tomm34 Purified

Spezifität: The mouse monoclonal antibody Tomm34-4.1 recognizes an epitope within TPR2 domain of human Tomm34 protein.

Aufreinigung: Purified by protein-A affinity chromatography.

Immunogen: Recombinant human Tomm34

Klon: Tomm34-4-1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu TOMM34

Target: TOMM34 (Translocase of Outer Mitochondrial Membrane 34 (TOMM34))

Andere Bezeichnung: Tomm34 (TOMM34 Produkte)

Synonyme: HTOM34P antikoerper, TOM34 antikoerper, URCC3 antikoerper, 2610100K07Rik antikoerper, Tomm34a antikoerper, Tomm34b antikoerper, zC239J9.1 antikoerper, zgc:56645 antikoerper, wu:fb96b08 antikoerper, TOMM34 antikoerper, translocase of outer mitochondrial membrane 34 antikoerper, TOMM34 antikoerper, Tomm34 antikoerper, tomm34 antikoerper, LOC100305086 antikoerper

Hintergrund: Translocase of outer mitochondrial membrane 34,Tomm34 (translocase of the outer mitochondrial membrane 34) is an additional component of the cellular chaperone system involved in protein folding. As the name suggests, Tomm34 was initially identified as being involved in mitochondrial protein processing. Subsequent studies have shown that Tomm34 interacts with both Hsp70 and Hsp90 and modifies their protein folding activities. In cancer, high levels of Tomm34 have been reported in bladder, colorectal and breast cancers compared to their normal tissue counterparts. In these cancers, Tomm34 promotes colorectal cancer cell growth and is a biomarker of poor outcome in early invasive breast cancer and bladder cancer. As a tumour-associated protein, Tomm34 peptide vaccination is under investigation as a therapeutic option for colorectal cancer, with significant Tomm34 cytotoxic T-lymphocyte (CTL) response observed.,URCC3, HTOM34P

Gen-ID: 10953

UniProt: Q15785