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TACSTD2 Antikörper

Name: TACSTD2 Antikörper
Brand: antibodies-online
SKU: ABIN7506026
Price: 288.42 EUR
Availability: InStock

TACSTD2 Reaktivität: Human, Schwein WB, IHC, FACS, ICC Wirt: Maus Monoclonal TrMab-6 unconjugated

Western blotting analysis of human TROP2 using mouse monoclonal antibody TrMab-6 on lysates of MCF-7, SK-BR-3, and HaCaT cell lines, TROP2-positive and TROP2-negative DU-145 cells, wild-type T-47D and TROP2 knock-out T-47D cells, and TROP2 over-expressing and knock-out MDA-MB-231 cells. (TACSTD2 Antikörper)

Immunohistochemistry staining (paraffin sections) of TROP2 in human and porcine lung tissue using mouse monoclonal antibody TrMab-6 (diluted 1:100), detected with En Vision FLEX/HRP. (TACSTD2 Antikörper)

IHC (p)

Separation of A431 cells (red-filled) from human peripheral whole blood cells (black-dashed) in flow cytometry analysis (surface staining) stained using anti-human TROP-2 (TrMab-6) purified antibody (concentration in sample 1,7 μg/mL, GAM APC). (TACSTD2 Antikörper)

FACS

Immunocytochemistry staining of TROP2 on the surface of unfixed wild-type and TROP2-overexpressing MDA-MB-231 cells using mouse monoclonal antibody TrMab-6 (1 μg/mL), detected with GAM IgG-Alexa Fluor488 (diluted 1:1000, green), isotype control IgG2b was used as the negative control. (TACSTD2 Antikörper)

ICC

4 Abbildungen

Produktnummer ABIN7506026

Datenblatt (PDF)

Target Alle TACSTD2 Antikörper anzeigen

TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))
Reaktivität
64

52

17

6
Human, Schwein
Wirt
61

17

3

1
Maus
Passende Sekundärantikörper
Klonalität
59

23
Monoklonal
Konjugat
37

7

6

4

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser TACSTD2 Antikörper ist unkonjugiert
Applikation
60

34

27

21

13

13

7

6

6

4

3

2

2

2

1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Verwendungszweck

Anti-Hu TROP2 Purified

Spezifität

The mouse monoclonal antibody TrMab-6 recognizes an extracellular epitope of TROP2, a type I transmembrane glycoprotein. This antibody is usefull for detection of TROP2 in breast cancer.

Keine Kreuzreaktivität

Maus

Aufreinigung

Purified by protein-A affinity chromatography.

Immunogen

TROP2-transfected CHO cells

Klon

TrMab-6

Isotyp

IgG2b kappa

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Applikationshinweise

Flow cytometry: Recommended dilution: 1-4 μg/mL.
Western blotting: Recommended dilution: 1 μg/mL.
Immunocytochemistry: Recommended dilution: 10 μg/mL, the cells can be fixed with 4 % PFA and permeabilized with 0.1 % Triton X-100 before antibody staining, when needed.
Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL. Heat-mediated antigen retrieval in citrate buffer, pH = 6.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1 mg/mL

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Informationen zur Lagerung

Store at 2-8°C. Do not freeze.
Target

TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Andere Bezeichnung

TROP2 (TACSTD2 Produkte)

Synonyme

EGP-1 antikoerper, EGP1 antikoerper, GA733-1 antikoerper, GA7331 antikoerper, GP50 antikoerper, M1S1 antikoerper, TROP2 antikoerper, C80403 antikoerper, Ly97 antikoerper, Prp1 antikoerper, tumor associated calcium signal transducer 2 antikoerper, tumor-associated calcium signal transducer 2 antikoerper, TACSTD2 antikoerper, Tacstd2 antikoerper

Hintergrund

Tumor associated calcium signal transducer 2,TROP2 is a cell surface receptor that transduces calcium signals. It belongs to carcinoma-associated antigens. Mutations of TROP2 have been associated with gelatinous drop-like corneal dystrophy.,TACSTD2, EGP1, GP50, M1S1, GA733-1

Gen-ID

4070

UniProt

P09758