MIA2 Antikörper (AA 268-360)

Produktnummer ABIN721150

Produktdetails anti-MIA2 Antikörper

Target: MIA2 (Melanoma Inhibitory Activity Protein 2 (MIA2))

Bindungsspezifität: AA 268-360

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MIA2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CTAGE5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu MIA2

Target: MIA2 (Melanoma Inhibitory Activity Protein 2 (MIA2))

Andere Bezeichnung: CTAGE5 (MIA2 Produkte)

Synonyme: MEA6 antikoerper, MGEA antikoerper, MGEA11 antikoerper, MGEA6 antikoerper, zgc:56047 antikoerper, melanoma inhibitory activity 2 antikoerper, CTAGE family, member 5 antikoerper, CTAGE family member 5, ER export factor antikoerper, MIA2 antikoerper, ctage5 antikoerper, CTAGE5 antikoerper, Mia2 antikoerper

Hintergrund:

Synonyms: cTAGE 5A, cTAGE 5B, cTAGE 5C, cTAGE 5D, cTAGE family member 5, CTAGE family, member 5, CTAGE5, cTAGE5A, cTAGE5B, cTAGE5C, cTAGE5D, CTGE5_HUMAN, Cutaneous T cell lymphoma associated antigen 5, Cutaneous T-cell lymphoma-associated antigen 5, MEA11, MEA6, Meningioma expressed antigen 6 coiled coil proline rich, Meningioma expressed antigen 6/11, Meningioma-expressed antigen 6/11, MGEA, MGEA11, MGEA6, Protein cTAGE 5, Protein cTAGE-5.

Background: Cutaneous T cell lymphomas (CTCL) represent a group of malignancies that originate from CD4-T lymphocytes and manifest on the skin. CTCL is a general term for several neoplasms including mycosis fungoides, T cell leukemia/ lymphoma and pagetoid reticulosis, all of which are very difficult to treat in the advanced stages. CTAGE2 (cutaneous T cell lymphoma associated-antigen 2) is a member of the cancer/testis antigen family of proteins (CTAGE) that, under normal conditions, are found primarily in the testis with little or no expression in other parts of the body. Another member of the CTAG family, namely CTAGE5 (also known as MEA11, MEA6, MGEA11 or MGEA6), is a tumor associated antigen that is found in tumors of various origins, including cutaneous T cell lymphomas. Both CTAGE2 and CTAGE5 are expressed as multiple isoforms due to alternative splicing events.

Gen-ID: 4253