MUM1 Antikörper (AA 401-500)

Produktnummer ABIN721195

Produktdetails anti-MUM1 Antikörper

Target: MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))

Bindungsspezifität: AA 401-500

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MUM1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-MUM1 Antikörper (ABIN721195)

Perez-Chacon, Adrados, Vallejo-Cremades, Lefebvre, Reed, Zapata: "Dysregulated TRAF3 and BCL2 Expression Promotes Multiple Classes of Mature Non-hodgkin B Cell Lymphoma in Mice." in: Frontiers in immunology, Vol. 9, pp. 3114, (2018) (PubMed).

Details zu MUM1

Target: MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))

Andere Bezeichnung: MUM1 (MUM1 Produkte)

Synonyme: EXPAND1 antikoerper, HSPC211 antikoerper, MUM-1 antikoerper, IRF4 antikoerper, 2610019J09 antikoerper, 9430059D04Rik antikoerper, UBE-1C2 antikoerper, melanoma associated antigen (mutated) 1 antikoerper, PWWP domain-containing protein MUM1 antikoerper, MUM1 antikoerper, LOC612320 antikoerper, Mum1 antikoerper

Hintergrund:

Synonyms: EXPAND1, FLJ14868, FLJ22283, HSPC211, Melanoma associated antigen mutated 1, Melanoma ubiquitous mutated protein, MGC131891, MGC163315, MUM 1, MUM-1, MUM1, MUM1_HUMAN, Mutated melanoma associated antigen 1, Mutated melanoma-associated antigen 1, Protein expandere, PWWP domain containing protein MUM1, PWWP domain-containing protein MUM1.

Background: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.

Gen-ID: 84939

Pathways: Chromatin Binding