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RNF43 Antikörper (AA 41-140)

RNF43 Reaktivität: Human, Maus ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN721600
  • Target Alle RNF43 Antikörper anzeigen
    RNF43 (Ring Finger Protein 43 (RNF43))
    Bindungsspezifität
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 41-140
    Reaktivität
    • 22
    • 10
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 23
    Kaninchen
    Klonalität
    • 23
    Polyklonal
    Konjugat
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RNF43 Antikörper ist unkonjugiert
    Applikation
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Cow,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RNF43
    Isotyp
    IgG
    Top Product
    Discover our top product RNF43 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    RNF43 (Ring Finger Protein 43 (RNF43))
    Andere Bezeichnung
    RNF43 (RNF43 Produkte)
    Synonyme
    RNF124 antikoerper, URCC antikoerper, 4732452J19Rik antikoerper, RGD1305204 antikoerper, ring finger protein 43 antikoerper, RNF43 antikoerper, Rnf43 antikoerper
    Hintergrund

    Synonyms: URCC, RNF124, E3 ubiquitin-protein ligase RNF43, RING finger protein 43, RNF43

    Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.

    Gen-ID
    54894
    UniProt
    Q68DV7
    Pathways
    WNT Signalweg
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