Rekombinanter 4-1BB (Utomilumab Biosimilar) Antikörper

Produktnummer ABIN7538049

Der Human Monoklonal Anti-4-1BB (Utomilumab Biosimilar)-Antikörper wurde für ELISA und WB validiert. Er ist geeignet, 4-1BB (Utomilumab Biosimilar) in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter 4-1BB (Utomilumab Biosimilar) Antikörper (ABIN7538049)

Target: 4-1BB (Utomilumab Biosimilar)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Human

Klonalität: Monoklonal

Konjugat: Dieser 4-1BB (Utomilumab Biosimilar) Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Güteklasse: Research Grade

Produktdetails anti-4-1BB (Utomilumab Biosimilar) Antikörper

Expressionssystem: Mammalian cells

Verwendungszweck: Utomilumab Biosimilar - Anti-Human TNFRSF9 mAb - Research Grade

Produktmerkmale: Antibody Type: IgG2 kappa

Aufreinigung: Recombinant antibody expressed in mammalien cells and purified.

Reinheit: > 85%

Isotyp: IgG2

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS pH 7.5

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C for short term, -20°C for long term

Details zu 4-1BB (Utomilumab Biosimilar)

Target: 4-1BB (Utomilumab Biosimilar)

Hintergrund: Utomilumab is a monoclonal antibody that binds to 4-IBB protein (also known as CD137 protein). 4-IBB protein is a receptor found in different immune cells such as helper T-cells, killer T-cells and natural killer cells. 4-IBB/CD137 protein is a costimulatory receptor whose activation results in a series of events that leads to cytokine secretion and effector functions. Hence, targeting CD137 protein has been linked to antitumor immunity response and overall tumor reduction. Indeed, once utomilumab is injected in the bloodstream its specific binding to CD137 protein stimulates the immune cells which, as a result, enhances the immune response against tumors.

CAS-Nummer: 1417318-27-4