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GLMN Antikörper (AA 151-250)

GLMN Reaktivität: Human WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN721945
  • Target Alle GLMN Antikörper anzeigen
    GLMN (Glomulin, FKBP Associated Protein (GLMN))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    Reaktivität
    • 54
    • 9
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Human
    Wirt
    • 50
    • 5
    Kaninchen
    Klonalität
    • 52
    • 3
    Polyklonal
    Konjugat
    • 24
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GLMN Antikörper ist unkonjugiert
    Applikation
    • 49
    • 27
    • 19
    • 14
    • 12
    • 12
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Dog,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FK506 binding protein associated protein
    Isotyp
    IgG
    Top Product
    Discover our top product GLMN Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    GLMN (Glomulin, FKBP Associated Protein (GLMN))
    Andere Bezeichnung
    FK506 binding protein associated protein (GLMN Produkte)
    Synonyme
    FAP antikoerper, FAP48 antikoerper, FAP68 antikoerper, FKBPAP antikoerper, GLML antikoerper, GVM antikoerper, VMGLOM antikoerper, 9330160J16Rik antikoerper, AW227515 antikoerper, Fap48 antikoerper, Fap68 antikoerper, MGC69174 antikoerper, GLMN antikoerper, zgc:194957 antikoerper, glmnl antikoerper, zgc:101567 antikoerper, glomulin, FKBP associated protein antikoerper, glomulin, FKBP associated protein L homeolog antikoerper, glomulin, FKBP associated protein b antikoerper, glomulin, FKBP associated protein a antikoerper, GLMN antikoerper, Glmn antikoerper, glmn.L antikoerper, glmn antikoerper, glmnb antikoerper, glmna antikoerper
    Hintergrund

    Synonyms: FAP, GVM, GLML, FAP48, FAP68, FKBPAP, VMGLOM, Glomulin, FK506-binding protein-associated protein, FKBP-associated protein, GLMN, GLMN_HUMAN

    Background: Isoform 1: Regulatory component of cullin-RING-based SCF (SKP1-Cullin-F-box protein) E3 ubiquitin-protein ligase complexes.). Inhibits E3 ubiquitin ligase activity by binding to RBX1 (via RING domain) and inhibiting its interaction with the E2 ubiquitin-conjugating enzyme CDC34. Inhibits RBX1-mediated neddylation of CUL1. Required for normal stability and normal cellular levels of key components of SCF ubiquitin ligase complexes, including FBXW7, RBX1, CUL1, CUL2, CUL3, CUL4A, and thereby contributes to the regulation of CCNE1 and MYC levels (By similarity). Essential for normal development of the vasculature. Contributes to the regulation of RPS6KB1 phosphorylation

    Gen-ID
    11146
    UniProt
    Q92990
    Pathways
    Tube Formation
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