GLMN Antikörper (AA 151-250) (Biotin)
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- Target Alle GLMN Antikörper anzeigen
- GLMN (Glomulin, FKBP Associated Protein (GLMN))
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Bindungsspezifität
- AA 151-250
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GLMN Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat,Dog,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human FK506 binding protein associated protein
- Isotyp
- IgG
- Top Product
- Discover our top product GLMN Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- GLMN (Glomulin, FKBP Associated Protein (GLMN))
- Andere Bezeichnung
- FK506 binding protein associated protein (GLMN Produkte)
- Hintergrund
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Synonyms: FAP, GVM, GLML, FAP48, FAP68, FKBPAP, VMGLOM, Glomulin, FK506-binding protein-associated protein, FKBP-associated protein, GLMN, GLMN_HUMAN
Background: Isoform 1: Regulatory component of cullin-RING-based SCF (SKP1-Cullin-F-box protein) E3 ubiquitin-protein ligase complexes.). Inhibits E3 ubiquitin ligase activity by binding to RBX1 (via RING domain) and inhibiting its interaction with the E2 ubiquitin-conjugating enzyme CDC34. Inhibits RBX1-mediated neddylation of CUL1. Required for normal stability and normal cellular levels of key components of SCF ubiquitin ligase complexes, including FBXW7, RBX1, CUL1, CUL2, CUL3, CUL4A, and thereby contributes to the regulation of CCNE1 and MYC levels (By similarity). Essential for normal development of the vasculature. Contributes to the regulation of RPS6KB1 phosphorylation
- Gen-ID
- 11146
- UniProt
- Q92990
- Pathways
- Tube Formation
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