GLMN Antikörper (AA 151-250) (Biotin)

Produktnummer ABIN721947

Produktdetails anti-GLMN Antikörper (Biotin)

Target: GLMN (Glomulin, FKBP Associated Protein (GLMN))

Bindungsspezifität: AA 151-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLMN Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FK506 binding protein associated protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu GLMN

Target: GLMN (Glomulin, FKBP Associated Protein (GLMN))

Andere Bezeichnung: FK506 binding protein associated protein (GLMN Produkte)

Synonyme: FAP antikoerper, FAP48 antikoerper, FAP68 antikoerper, FKBPAP antikoerper, GLML antikoerper, GVM antikoerper, VMGLOM antikoerper, 9330160J16Rik antikoerper, AW227515 antikoerper, Fap48 antikoerper, Fap68 antikoerper, MGC69174 antikoerper, GLMN antikoerper, zgc:194957 antikoerper, glmnl antikoerper, zgc:101567 antikoerper, glomulin, FKBP associated protein antikoerper, glomulin, FKBP associated protein L homeolog antikoerper, glomulin, FKBP associated protein b antikoerper, glomulin, FKBP associated protein a antikoerper, GLMN antikoerper, Glmn antikoerper, glmn.L antikoerper, glmn antikoerper, glmnb antikoerper, glmna antikoerper

Hintergrund:

Synonyms: FAP, GVM, GLML, FAP48, FAP68, FKBPAP, VMGLOM, Glomulin, FK506-binding protein-associated protein, FKBP-associated protein, GLMN, GLMN_HUMAN

Background: Isoform 1: Regulatory component of cullin-RING-based SCF (SKP1-Cullin-F-box protein) E3 ubiquitin-protein ligase complexes.). Inhibits E3 ubiquitin ligase activity by binding to RBX1 (via RING domain) and inhibiting its interaction with the E2 ubiquitin-conjugating enzyme CDC34. Inhibits RBX1-mediated neddylation of CUL1. Required for normal stability and normal cellular levels of key components of SCF ubiquitin ligase complexes, including FBXW7, RBX1, CUL1, CUL2, CUL3, CUL4A, and thereby contributes to the regulation of CCNE1 and MYC levels (By similarity). Essential for normal development of the vasculature. Contributes to the regulation of RPS6KB1 phosphorylation

Gen-ID: 11146

UniProt: Q92990

Pathways: Tube Formation