Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

FcRn Antikörper

FcRn Reaktivität: Human ELISA, IF, FACS, cELISA, Func Wirt: Maus Monoclonal ADM31 unconjugated
Produktnummer ABIN7539617
  • Target Alle FcRn Antikörper anzeigen
    FcRn (IgG receptor FcRn (FcRn))
    Reaktivität
    • 42
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 39
    • 8
    • 1
    Maus
    Klonalität
    • 40
    • 8
    Monoklonal
    Konjugat
    • 23
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FcRn Antikörper ist unkonjugiert
    Applikation
    • 30
    • 27
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Cell-ELISA (cELISA), Functional Studies (Func)
    Produktmerkmale
    based on recognition of the complete native protein expressed on transfected mammalian cells
    Aufreinigung
    Purified, Protein G
    Immunogen
    hFcRn
    Klon
    ADM31
    Isotyp
    IgG2b lambda
    Top Product
    Discover our top product FcRn Primärantikörper
  • Applikationshinweise
    • Flow cytometry: 1.2 μg/10^6 cells
    • ELISA: 1:200 - 1:400
    • CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS pH 7.2 with 50% glycerol
    Handhabung
    avoid repeated freezing and thawing
    Lagerung
    4 °C
  • Target
    FcRn (IgG receptor FcRn (FcRn))
    Andere Bezeichnung
    Fc Receptor (FcRn) FcRn (FcRn Produkte)
    Synonyme
    FCRN antikoerper, alpha-chain antikoerper, FcRn antikoerper, Fc fragment of IgG receptor and transporter antikoerper, Fc receptor, IgG, alpha chain transporter antikoerper, FCGRT antikoerper, Fcgrt antikoerper
    Hintergrund
    The MHC class I-like Fc receptor (FcRn) is an intracellular trafficking Fc receptor that is uniquely responsible for the extended serum half-life of antibodies of the IgG subclass and their ability to transport across cellular barriers. By performing these functions, FcRn affects numerous facets of antibody biology and pathobiology. Its critical role in controlling IgG pharmacokinetics has been leveraged for the design of therapeutic antibodies and related biologics. FcRn also traffics serum albumin and is responsible for the enhanced pharmacokinetic properties of albumin-conjugated therapeutics.
    Synonyms: IgG receptor FcRn large subunit p51, Neonatal Fc receptor, FCGRT
    UniProt
    P55899
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Sie sind hier:
Kundenservice