FcRn Antikörper
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- Target Alle FcRn Antikörper anzeigen
- FcRn (IgG receptor FcRn (FcRn))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser FcRn Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Cell-ELISA (cELISA)
- Produktmerkmale
- based on recognition of the complete native protein expressed on transfected mammalian cells
- Aufreinigung
- Purified, Protein G
- Immunogen
- hFcRn
- Klon
- DVN24
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product FcRn Primärantikörper
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anti-IgG receptor FcRn (FcRn) antibody
FcRn Reaktivität: Human ELISA, IF, FACS, cELISA, Func Wirt: Maus Monoclonal ADM31 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-297) antibodyFcRn Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-IgG receptor FcRn (FcRn) antibodyFcRn Reaktivität: Human ELISA, IF, FACS, cELISA Wirt: Maus Monoclonal DVN24 unconjugated
anti-IgG receptor FcRn (FcRn) antibodyFcRn Reaktivität: Human ELISA, IF, FACS, cELISA, Func Wirt: Maus Monoclonal ADM31 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-365) antibodyFcRn Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-297) antibodyFcRn Reaktivität: Human WB, ELISA, IHC, ICC, FACS, Neut Wirt: Maus Monoclonal 2B3B11 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-297) antibodyFcRn Reaktivität: Human WB, ELISA, IHC, ICC, FACS, Neut Wirt: Maus Monoclonal 5F3D1 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-215) antibodyFcRn Reaktivität: Human IHC, ISt, StM Wirt: Maus Monoclonal FCGRT-2932 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 330-357), (C-Term) antibodyFcRn Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB39368 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 25-300) antibodyFcRn Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Flow cytometry: 1.2 μg/10^6 cells ELISA: 1:200 - 1:400CELISA: 1:200 - 1:400For each application a titration should be performed to determine the optimal concentration.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS pH 7.2 with 50% glycerol
- Handhabung
- avoid repeated freezing and thawing
- Lagerung
- 4 °C
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- Target
- FcRn (IgG receptor FcRn (FcRn))
- Andere Bezeichnung
- Fc Receptor (FcRn) FcRn (FcRn Produkte)
- Synonyme
- FCRN antikoerper, alpha-chain antikoerper, FcRn antikoerper, Fc fragment of IgG receptor and transporter antikoerper, Fc receptor, IgG, alpha chain transporter antikoerper, FCGRT antikoerper, Fcgrt antikoerper
- Hintergrund
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The MHC class I-like Fc receptor (FcRn) is an intracellular trafficking Fc receptor that is uniquely responsible for the extended serum half-life of antibodies of the IgG subclass and their ability to transport across cellular barriers. By performing these functions, FcRn affects numerous facets of antibody biology and pathobiology. Its critical role in controlling IgG pharmacokinetics has been leveraged for the design of therapeutic antibodies and related biologics. FcRn also traffics serum albumin and is responsible for the enhanced pharmacokinetic properties of albumin-conjugated therapeutics.
Synonyms: IgG receptor FcRn large subunit p51, Neonatal Fc receptor, FCGRT - UniProt
- P55899
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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