DCLK2 Antikörper (AA 652-766)
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- Target Alle DCLK2 Antikörper anzeigen
- DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))
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Bindungsspezifität
- AA 652-766
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser DCLK2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Verwendungszweck
- DCLK2 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human DCLK2 (AA: 652-766) expressed in mammalian.
- Klon
- 3H1G4
- Isotyp
- IgG2a
- Top Product
- Discover our top product DCLK2 Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))
- Andere Bezeichnung
- DCLK2 (DCLK2 Produkte)
- Synonyme
- CL2 antikoerper, CLICK-II antikoerper, CLICK2 antikoerper, CLIK2 antikoerper, DCAMKL2 antikoerper, DCDC3 antikoerper, DCDC3B antikoerper, DCK2 antikoerper, 6330415M09Rik antikoerper, AU044875 antikoerper, Click-II antikoerper, Dcamkl2 antikoerper, DCLK2 antikoerper, cb572 antikoerper, dclk antikoerper, sb:cb572 antikoerper, si:dkey-180n16.1 antikoerper, Dck2 antikoerper, RGD1308384 antikoerper, doublecortin like kinase 2 antikoerper, doublecortin-like kinase 2 antikoerper, doublecortin-like kinase 2a antikoerper, DCLK2 antikoerper, Dclk2 antikoerper, dclk2a antikoerper
- Hintergrund
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Description: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.
Aliases: CL2, DCK2, CLIK2, DCDC3, CLICK2, DCDC3B, DCAMKL2, CLICK-II
- Molekulargewicht
- 83.6 kDa
- Gen-ID
- 166614
- UniProt
- Q8N568
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