SH2B2 Antikörper (AA 497-676)

Produktnummer ABIN7539759

Produktdetails anti-SH2B2 Antikörper

Target: SH2B2 (SH2B Adaptor Protein 2 (SH2B2))

Bindungsspezifität: AA 497-676

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SH2B2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Verwendungszweck: SH2B2 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human SH2B2 (AA: 497-676) expressed in E. Coli.

Klon: 5E11G7

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu SH2B2

Target: SH2B2 (SH2B Adaptor Protein 2 (SH2B2))

Andere Bezeichnung: SH2B2 (SH2B2 Produkte)

Synonyme: APS antikoerper, Aps antikoerper, SH2B adaptor protein 2 antikoerper, SH2B2 antikoerper, Sh2b2 antikoerper

Hintergrund:

Description: The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.

Aliases: APS

Molekulargewicht: 67.7 kDa

Gen-ID: 10603

UniProt: O14492

Pathways: Carbohydrate Homeostasis, Brown Fat Cell Differentiation