ADAM10 Antikörper (APC)
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- Target Alle ADAM10 Antikörper anzeigen
- ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ADAM10 Antikörper ist konjugiert mit APC
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Applikation
- Flow Cytometry (FACS)
- Verwendungszweck
- Anti-Hu CD156c APC
- Spezifität
- The mouse monoclonal antibody 11G2 recognizes an extracellular/luminal epitope of CD156c, a type I transmembrane glycoprotein, serving as a zinc-dependent metalloprotease.
- Keine Kreuzreaktivität
- Maus
- Aufreinigung
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogen
- Jurkat cells
- Klon
- 11G2
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product ADAM10 Primärantikörper
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- Applikationshinweise
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Target
- ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
- Andere Bezeichnung
- CD156c (ADAM10 Produkte)
- Hintergrund
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NCBI Full Gene Name: ADAM metallopeptidase domain 10
Description: CD156c is a type I transmembrane glycoprotein with a zinc-dependent metalloprotease activity. It serves as an endopeptidase of broad specificity, which is expressed mainly in thymus, liver, and muscles. Its expression can be induced in inflamed central nervous system, and in arthritic tissues. CD156c is involved in multiple sclerosis-associated myelin degradation. It also solubilizes various membrane proteins, including CD23, CD44, CD126, CD171, ephrin-A2, and other.
Other names: ADAM10, AD10, RAK, MADM, HsT18717
Gene name: ADAM10
- Gen-ID
- 102
- UniProt
- O14672
- Pathways
- Notch Signalweg, EGFR Signaling Pathway
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